Amazing Spider Man Comic 6
Andrew Garfield faced off against The Lizard in his first Amazing Spider-Man movie in 2012. The Lizard, along with Garfield himself, made his comeback in No Way Home.
Lizard is one of the all-time greats on the Spider-Man villains list. His first appearance is a big key issue; he would not appear in the comic again for several years.
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From the first appearance in Amazing Fantasy #15 to modern keys like the first Carnage, if it's a Spidey key, then it's here.
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